Cancrum Oris Noma

Authored by , Reviewed by Dr Hannah Gronow on

This article is for Medical Professionals

Professional Reference articles are designed for health professionals to use. They are written by UK doctors and based on research evidence, UK and European Guidelines. You may find one of our health articles more useful.

This page has been archived. It has not been updated since 19/08/2011. External links and references may no longer work.

Synonyms: noma (from Greek: to devour); gangrenous stomatitis; face of poverty (flourishes where poverty is rife)

This was described in the mid-eighteenth century by Tourdes. It describes spontaneous necrosis of the soft and hard tissues of the oral cavity. Other oral problems are outlined in the related separate article Problems in the Mouth.

A disease of children (80% of patients are less than 10 years old), it is seen in developing countries, especially the poorest areas of Africa, some parts of Asia and South America.[1] The World Health Organization (WHO) estimates that 100,000 people are affected per year - of which 80% are children in Africa.

Some cultures do not treat the disease, as it is considered taboo. This results in a barrier to detection of the disorder and to its appropriate management.

The cause is unknown but it may develop secondary to acute necrotising fasciitis.

Risk factors

  • Prior to necrosis:
    • Poor oral hygiene is nearly always present.
    • Excessive salivation.
    • Malodour from the mouth.
    • Grey discoloration.
    • Gingival ulcer formation.
  • Followed by rapid, painless and extensive necrosis of the oral cavity, which can involve the cheek, nose, palate and bones.

In 'noma pudendi' there is necrosis of the genitalia and, in 'noma neonatorum', mucocutaneous gangrene occurs during the neonatal period.[2]

  • Swabs and culture for organisms - Borrelia vincentii and fusiform bacilli are commonly found, as are anaerobes in rapidly progressing cases.[3]
  • Facial X-rays and CT scan to determine the extent of involvement.
  • Resuscitation - airway protection may be needed; fluid resuscitation to prevent dehydration.
  • Antibiotics.
  • Enteral feeding.
  • Patients usually require wound debridement.
  • Later treatment requires plastic surgery with facial reconstruction and possible repair of temporomandibular joint.[4]
  • Dehydration
  • Sepsis
  • Airway compromise
  • Facial disfigurement
  • Psychological stress

The clinical course varies with each case and there is a high morbidity and mortality rate. WHO estimates that 70-90% of cases die.[4]

Further reading and references

  1. ; Cases of Noma reported in regions of the world, World Health Organization

  2. ; Noma neonatorum. Indian J Pediatr. 2006 May73(5):439-40.

  3. ; Prevalent bacterial species and novel phylotypes in advanced noma lesions. J Clin Microbiol. 2002 Jun40(6):2187-91.

  4. ; Noma--the ulcer of extreme poverty. N Engl J Med. 2006 Jan 19354(3):221-4.

Red patch on tongue, has varied in color over the past 2 weeks. Some days I feel like it’s fading, other days it seems red, maybe irritated by food. Located on front side of tongue. I feel like I...

j27940
Health Tools

Feeling unwell?

Assess your symptoms online with our free symptom checker.

Start symptom checker
cost of surrogacy uk

read here

www.best-cooler.reviews