Folic Acid Deficiency Anaemia

Authored by , Reviewed by Dr Jacqueline Payne on | Certified by The Information Standard

A normal balanced diet contains enough folic acid. However, a lack of folic acid will cause anaemia and sometimes other symptoms.

Folic acid (folate) is a vitamin and is needed to make new cells in your body, including red blood cells. Your body does not store very much folic acid. You need a regular fresh supply to keep healthy.

A blood test can confirm anaemia due to folic acid deficiency. It is also very common to have a blood test for your vitamin B12 levels as these can also be low. Read more in the separate leaflet called Vitamin B12 Deficiency and Pernicious Anaemia.

Symptoms due to anaemia are caused by the reduced amount of oxygen in the body.

  • Common symptoms include tiredness, having little energy (lethargy), feeling faint and becoming easily breathless.
  • Less common symptoms include headaches, heartbeats suddenly becoming noticeable (palpitations), altered taste and ringing in your ears (tinnitus).
  • You may look pale.

Other symptoms may include numbness in your hands and feet. Some people may also have depression.

Treatment is easy and is by taking a tablet of folic acid (folate) each day. You need to take this until the anaemia is corrected and the folic acid stores in the body are built up (usually for about four months). You may need advice on diet to stay well and the tablets can be stopped if your diet improves. You may need to continue with treatment if a poor diet was not the cause of folic acid deficiency. For example, if you have sickle cell disease you may need a folic acid tablet each day indefinitely. Find out more about diets suitable for people with anaemia.

Extra folic acid (folate) is advised for at least the first 12 weeks of pregnancy for all women - even if you are healthy and have a good diet. If you take extra folic acid in early pregnancy you have less chance of having a baby born with a spinal cord problem such as spina bifida. It is best to start taking the extra folic acid before becoming pregnant. If the pregnancy is unplanned then start taking folic acid as soon as you know you are pregnant. You can buy folic acid tablets at most health food shops or pharmacies.

  • For most women the dose is 400 micrograms (0.4 mg) a day.
  • If your risk of having a child with a spinal cord problem is increased then the dose is higher (5 mg a day - you need a prescription for this higher dose). That is, if:
    • You have already had a previous baby with a spinal cord problem.
    • You, your partner or a first-degree relative have a spinal cord problem.
    • You have coeliac disease, diabetes, sickle cell anaemia or thalassaemia.
    • You are obese - especially if your body mass index (BMI) is 30 or more.
    • You are taking certain medication for epilepsy (your doctor will advise).

See also the separate leaflets called Planning to Become Pregnant and Diet and Lifestyle during Pregnancy.

Further reading and references

  • ; NICE CKS, February 2013 (UK access only)

  • ; European Society for Medical Oncology (2010)

  • ; British Committee for Standards in Haematology (2015)

  • ; The Renal Association, 2017

Signs you may have anaemia
Signs you're not getting enough vitamin B12

so .. i got a blood test done .. my iron showed LO. im not exactly sure how low it is so if anyone understands these numbers .. thatd be a bonus : RBC : me - 3.99 ... normal - 4.00hemoglobin: me - 115...

stephanie2000
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