Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Biphasic response in the secretion of gonadotropin-releasing hormone in ovariectomized ewes injected with oestradiol. Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat.
Cell-specific expression of the human gonadotropin-releasing hormone gene in transgenic animals. Estrogen signaling through the transmembrane G protein-coupled receptor GPR Laser-captured single digoxigenin-labeled neurons of gonadotropin-releasing hormone types reveal a novel G protein-coupled receptor Gpr54 during maturation in cichlid fish.
Not all water-soluble hormones initiate the cAMP second messenger system. Second messenger hormones that affect secondary sex characteristics male in Oregon greatly amplify the hormone signal, creating a broader, more efficient, and faster response. Estrogen receptor and progesterone receptor-immunoreactive cells are not co-localized with gonadotropin-releasing hormone in the brain of the female mink Mustela vison.
Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles. Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult. At the same time, estrogen greatly enhances the responsiveness of the gonadotrophs to this burst of GnRH Taga et al.
Another significant ovarian hormone is progesteronewhich contributes to regulation of the menstrual cycle and is important in preparing the body for pregnancy as well as maintaining pregnancy.
Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol. It also secretes human placental lactogen hPLwhich plays a role in preparing the breasts for lactation, and relaxin, which is thought to help soften and widen the pubic symphysis in preparation for childbirth.
An accumulating body of in vitro evidence currently indicates the presence of functional ERs in GnRH neurons. Feedback loops govern the initiation and maintenance of most hormone secretion in response to various stimuli. Endocrine defects in mice carrying a null mutation for the progesterone receptor gene.