Prognosis The prognosis of trisomy X is variable, with some individuals doing extremely well with minimal manifestations of the disorder, and others with more significant cognitive and psychological involvement as described above. Archived from the original on In trisomy X, a large percentage of the reported cases of POF have also been associated with other autoimmune diseases [ 232627 ], including autoimmune thyroid disorder [ 25 ].
Expanding the phenotype of triple X syndrome: A comparison of prenatal versus postnatal diagnosis. Seizures, renal and genitourinary abnormalities, and premature ovarian failure POF can also be associated findings. People normally have 46 chromosomes in each cell. Abnormalities on the electroencephalography may be present.
Please see Figure 1 for photographs of girls with trisomy X, and Table 1 for a summary of physical and medical features.
Behavioral and psychological features in girls and women with triple-x syndrome. Adolescents or adult females presenting with POF should be tested for trisomy X, Turner syndrome, and the fragile X premutation, and should have further evaluation to identify other possible medical causes of POF.
Trisomy X 47,XXX is a sex chromosome aneuploidy condition in which females have an extra X chromosome, compared to the 46,XX karyotype in typical females. Speech therapy, physical therapy, counseling .
Since the longitudinal studies of the 's and 80's of females with trisomy X followed into adulthood, there have been very few additional research studies focused exclusively on this genetic disorder. Diagnosis during the prenatal period by amniocentesis or chorionic villi sampling is common.
These chromosomes contain genes, which carry instructions that determine everything from height to eye color. However, due to the shift of the curve, a larger percentage of females with 47,XXX fall in the intellectual disability range compared to controls.
Attentional problems, poor executive function, and decreased adaptive functioning skills may also impact educational and home functioning.